CDH1 and SNAI1 are regulated by E7 from human papillomavirus types 16 and 18
نویسندگان
چکیده
منابع مشابه
Correlation of human papillomavirus type 16 and human papillomavirus type 18 e7 messenger RNA levels with degree of cervical dysplasia.
Infection with certain types of human papillomavirus (HPV) is a necessary event in the development of cervical carcinoma; however, not all women who become infected with HPV will progress to cancer. Much is known about the molecular influence of HPV E6 and E7 proteins on the malignant transformation. Little is known about the additional factors needed to drive the process. Quantitative real-tim...
متن کاملHuman papillomavirus type 16 E2 and E6/E7 variants.
OBJECTIVES Polymorphisms in human papillomavirus (HPV) type 16 have been shown to be related to geographic areas and are broadly classified as European (E), African (Af), Asian (As), or Asian-American (AA). Certain variants have been reported as being more likely to cause cervical disease; our objectives were to identify new HPV16 polymorphisms, to determine the linkage of the E2 and E6/E7 regi...
متن کاملPresence of Human Papillomavirus -16 and -18 Among Women with Breast Cancer in Isfahan Province
Background: Various studies proposed virus infection is to be a possible cause of human breast cancer. However, the data argue the association between virus and cancer are inconsistent. This study was conducted to detect whether HPV-DNA is present in tissue samples of breast cancer in Isfahan province. Materials and Methods: Paraffin embedded formalin fixed specimens were prepared from 40 brea...
متن کاملHuman papillomavirus 16/18 E7 viral loads predict distant metastasis in oral cavity squamous cell carcinoma.
BACKGROUND Human papillomaviruses (HPV) seem to be related to distant metastasis (DM) in advanced oral cavity squamous cell carcinoma (OSCC) patients. OBJECTIVES This study aimed to investigate whether high-risk HPV viral load may predict DM among OSCC patients and stratify patients for risk-adapted treatment. STUDY DESIGN Viral loads of E7 oncogenes for HPV 16/18 were measured by quantitat...
متن کاملPresence of E6 and E7 mRNA from human papillomavirus types 16, 18, 31, 33, and 45 in the majority of cervical carcinomas.
The oncogenic potential of the human papillomavirus (HPV) early genes E6 and E7 is well established and a source of interest with regard to HPV testing for cervical carcinoma. Here we present a study performed with 204 histologically confirmed invasive cervical squamous cell carcinomas (SCCs) in which we evaluated the HPV E6 and E7 mRNA detection assay PreTect HPV-Proofer for detection of high-...
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ژورنال
عنوان ژورنال: International Journal of Oncology
سال: 2020
ISSN: 1019-6439,1791-2423
DOI: 10.3892/ijo.2020.5039